Localization of the 5-HT1A receptor in lipid microdomains depends on its palmitoylation and is involved in receptor-mediated signalling
نویسندگان
چکیده
U.R., K.G., E.P., S.B., B.K., D.W.R. and E.P., Abteilung Neuround Sinnesphysiologie, Physiologisches Institut, Universität Göttingen, Humboldtallee 23, 37073 Göttingen, Germany; U.R., D.W.R. and E.P., Center of Molecular Physiology of the Brain, Göttingen, Germany; T.L. and R.J., Department of Neurobiology, Max-Plank-Institute for Biophysical Chemistry, D37077 Göttingen, Germany. Molecular Pharmacology Fast Forward. Published on May 31, 2007 as doi:10.1124/mol.107.037085
منابع مشابه
Localization of the mouse 5-hydroxytryptamine(1A) receptor in lipid microdomains depends on its palmitoylation and is involved in receptor-mediated signaling.
In the present study, we have used wild-type and palmitoylation-deficient mouse 5-hydroxytryptamine(1A) receptor (5-HT1A) receptors fused to the yellow fluorescent protein- and the cyan fluorescent protein (CFP)-tagged alpha(i3) subunit of heterotrimeric G-protein to study spatiotemporal distribution of the 5-HT1A-mediated signaling in living cells. We also addressed the question on the molecul...
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